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. Author manuscript; available in PMC: 2018 Jun 7.
Published in final edited form as: Cell Syst. 2018 Mar 21;6(4):456–469.e10. doi: 10.1016/j.cels.2018.02.004

Figure 7. Fold-Change Data from a Broad Collection of Different Strains Collapse onto a Single Master Curve.

Figure 7

(A) Any combination of parameters can be mapped to a single physiological response (i.e., fold-change) via the free energy, which encompasses the parametric details of the model.

(B) Experimental data from Figure 5 collapse onto a single master curve as a function of the free energy Equation 12. The free energy for each strain was calculated from Equation 12 using n = 2, ΔεAI = 4.5 kBT, KA = 139 × 10−6 M, KI = 0.53 × 10−6 M, and the strain-specific R and ΔεRA. All data points represent the mean, and error bars are the SEM for eight or more replicates.