Table 5.

Change in advanced lipoprotein characterization, glucose metabolism, and inflammation between baseline and end of open label extension

	Baseline (SD)	End of Study (SD)	Diff (SE)	p-value
TC	171.000 (37.159)	174.164 (34.347)	3.164 (4.216)	0.456
Efflux	1.088 (0.233)	0.871 (0.163)	−0.217 (0.032)	<0.001
LDL-P	1256.701 (395.937)	1279.239 (400.703)	22.537 (44.283)	0.613
HDL-P	33.299 (7.543)	30.315 (6.721)	−2.984 (0.786)	<0.001
Log Insulin	6.284 (0.911)	6.402 (0.795)	0.118 (0.136)	0.388
Log Adiponectin	2.240 (0.738)	2.166 (0.571)	−0.074 (0.068)	0.277
Log Leptin	9.110 (1.342)	9.158 (1.233)	0.048 (0.195)	0.808
Log CRP	15.412 (1.425)	14.597 (1.383)	−0.815 (0.192)	<0.001
Log TNF-alpha	0.688 (0.554)	0.413 (0.873)	−0.275 (0.131)	0.040
Log IL6	−0.820 (1.809)	0.234 (1.160)	1.054 (0.243)	<0.001
GlycA	399.742 (64.876)	370.184 (65.916)	−29.559 (7.749)	<0.001

(statistically significant findings bolded)