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. 2018 May 31;12:340. doi: 10.3389/fnins.2018.00340

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Copyright © 2018 Li, Huang, Lin, Liu, Zhang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between pain intensity and N2-P2 amplitude at Cz. Colored dots represent the N2-P2 amplitudes of fast-pain trials averaged across participants, and error bars denote the SD values across participants. The blue line represents the fitted linear model for low-pain trials and fast-pain trials separately. Note that, when NRS = 10, the N2-P2 amplitudes are slightly lower than those of NRS = 9. The possible reason is that only 18 participants had fast-pain trials of NRS = 10, which might make the estimation have large variance and not reliable.