Table 1.
General characteristics of the two populations
| Responder | Non-responders | P | |
| Number of patients | 14 | 7 | |
| Age (yr) | 67.2 (62, 75) | 68.2 (61, 77.7) | NS |
| Weight (kg) | 85 (75, 90) | 75 (61.8, 78.8) | NS |
| Body mass index | 26.5 (24.1, 27.8) | 25.9 (20.4, 28.5) | NS |
| Males | 12 (85.7%) | 4 (57.1%) | NS |
| Total days in ICU | 4.5 (3, 6) | 10 (9.3, 19.8)* | 0.016 |
| Total days in hospital | 13.5 (11, 30) | 23 (17.5, 39) | NS |
| Mortality at 28 d | 2 (15.4%)n=13 | 5 (71.4%)§ | 0.022 |
| Mortality at 100 d | 2 (20%)n=10 | 5 (71.4%) | NS |
| Source of infection | |||
| Respiratory | 3 (21.4%) | 3 (42.9%) | NS |
| Abdominal | 3 (21.4%) | 3 (42.9%) | NS |
| Urinary tract | 5 (35.8%) | 1 (14.3%) | NS |
| Others | 3 (21.4%) | 0 (0%) | NS |
| Comorbidities | |||
| Chronic organ insufficiency | 13 (92.9%) | 6 (85.7%) | NS |
| Arterial hypertension | 5 (35.7%) | 3 (42.9%) | NS |
| Diabetes | 0 (0%) | 1 (14.2%) | NS |
| Coronary disease | 1 (7.1%) | 0 (0%) | NS |
| Systolic/diastolic disease | 0 (0%) | 1 (14.3%) | NS |
| Cerebrovascular disease | 1 (7.1%) | 1 (14.3%) | NS |
| Peripheral vascular disease | 1 (7.1%) | 0 (0%) | NS |
| Chronic lung disease | 2 (14.3%) | 2 (28.6%) | NS |
| Inflammatory bowel disease | 0 (0%) | 0 (0%) | NS |
| Liver disease | 1 (7.1%) | 1 (14.3%) | NS |
| Chronic kidney disease | 0 (0%) | 0 (0%) | NS |
| Acute heart failure | 8 (57.1%) | 4 (57.1%) | NS |
| Prolonged arrhythmias | 1 (7.1%) | 1 (14.3%) | NS |
Numerical data are reported as median (25th, 75th) percentile; categorical data are expressed as number of cases (percentage). Comparisons between R and NR: *P < 0.05 (Mann–Whitney U test). Comparisons between R and NR: §P < 0.05 (Fisher exact test)