Table 1.

Hub Regions for Each Subject Group

Group	Hub type	Module	Region	MNI			Rank
				X	Y	Z	HC	Smokers
HC	Connector	ECa	L opercular	−51	8	−2	1	31
		SMb	L mid-cingulate	0	−15	47	1	2
		SUBc	R Putamen	31	−14	2	1	3
		VISd	R fusiform	27	−59	9	1	20
	Provincial	EC	L DMPFC	−2	38	36	1	5
		SM	L mid-cingulate	0	−15	47	1	13
		SUB	L hippocampus	−28	−18	−20	1	8
		VIS	R superior occipital	−18	−84	13	1	2
Smoker	Connector	EC	L ACC	−5	18	34	20	1
		SM	R precuneus	4	−48	51	20	1
		SUB	R parahippocampus	27	−37	−13	34	1
		VIS	L cuneus	−16	−77	34	3	1
	Provincial	EC	L middle frontal	−42	25	30	47	1
		SM	R postcentral	47	−30	49	35	1
		SUB	L hippocampus	−24	−12	−24	2	1
		VIS	L occipital pole	−24	−91	10	5	1

EC = executive control; HC = healthy nonsmoking controls; SM = sensorimotor; SUB = subcortical; VIS = Visual.

^a107 regions.

^b67 regions.

^c72 regions.

^d48 regions.