TABLE 3.
Change in postprandial plasma biomarker AUC in healthy obese and nonobese premenopausal women after consuming low-fat yogurt or control food followed by challenge meals at baseline and week 9 of the intervention1
| Week 9 – week 0 | Significance (P)2 | ||||||
|---|---|---|---|---|---|---|---|
| Δ AUC0–4h | CN | YN | CO | YO | Obesity | Treatment | Interaction |
| sCD14 (ng/mL · h) | −188 ± 155 | −292 ± 130 | −231 ± 106 | 114 ± 138 | 0.18 | 0.37 | 0.10 |
| LBP (μg/mL · h) | 2.48 ± 1.75 | −0.55 ± 1.41 | 0.07 ± 1.13 | −2.21 ± 1.36 | 0.16 | 0.065 | 0.79 |
| LBP:sCD14 | 3.54 ± 1.66 | 1.23 ± 1.30 | 1.61 ± 1.05 | −2.99 ± 1.16 | 0.020 | 0.0093 | 0.38 |
| IL-6 (pg/mL · h) | −0.16 ± 0.67 | 0.17 ± 0.55 | −0.25 ± 0.54 | −1.19 ± 0.49 | 0.20 | 0.59 | 0.27 |
| Glucose (mg/dL · h) | 3.56 ± 7.17 | 3.29 ± 8.67 | 16.8 ± 12.1 | 2.54 ± 7.98 | 0.50 | 0.43 | 0.45 |
| TG (mg/dL · h) | 122 ± 14 | 106 ± 15 | 150 ± 17 | 184 ± 22 | 0.72 | 0.64 | 0.98 |
1Data are means ± SEMs, n = 30. CN, control nonobese; CO, control obese; LBP, LPS-binding protein; sCD14, soluble CD14; YN, yogurt nonobese; YO, yogurt obese; Δ, difference.
2The effects of obesity status (obese compared with nonobese), dietary treatment (low-fat yogurt compared with control food), and the obesity × treatment interaction on changes in total AUC were determined by 2-factor ANOVA (PROC GLM).