Table 2.

Univariate analyses of lymph node metastases in patients with sporadic medullary thyroid carcinoma.

Factors	Total	Central compartment metastases			Lateral compartment metastases
		n (%)	χ2	pa	n (%)	χ2	pa
Sex
Male	27	16 (59.3)	3.192	0.074	14 (51.9)	2.703	0.100
Female	38	14 (36.8)			12 (31.6)
Age, years
≥45	45	21 (46.7)	0.015	0.901	19 (42.2)	0.301	0.583
<45	20	9 (45.0)			7 (35.0)
Tumor size
≥1 cm	45	24 (53.3)	3.859	0.049	23 (51.1)	8.547	0.003
<1 cm	20	6 (20.0)			3 (15.0)
Multifocality
Yes	17	13 (76.4)	8.514	0.004	11 (64.7)	5.855	0.016
No	48	17 (35.4)			15 (31.3)
Vascular invasion
Yes	22	8 (36.4)	1.283	0.257	8 (36.4)	2.637	0.104
No	43	22 (51.2)			18 (41.9)
Capsule invasion
Yes	26	21 (80.8)	20.893	<0.001	20 (76.9)	19.752	<0.001
No	39	9 (25.0)			6 (15.4)

^aResults of chi-square test between lymph node involvement and tumor characteristics.