Table 2.

Comparison between different diagnostic modalities.

	Accuracy	Specificity	Sensitivity	Indication	Limitation
MDCT	40–50%	60–90%	50–90%	Basic staging study	Lacks accuracy in neo- adjuvant and follow – up setting
MRI	70–80%	70–90%	55–75%	Similar benefits to MDCTNewer modalities (DWI sequence, newer contrast agents) have the potential to increase accuracy	Not widely availableSome of its characteristics are still under investigationExpensive
EUS	50–80%	80–90%	70–80%	Accurate for regional lymph nodesAddition of FNA offers tissue confirmation	Inadequate for distal metastasesOperator – dependentInherent limitations in certain anatomic areas
PET	30–40%	40–50%	>90%	High sensitivityDetects distant metastases with higher sensitivity than other modalities	Inadequate for loco – regional diseaseHigh rate of false positive resultsExpensiveNot widely available