Table 3. Non-displaceable binding potentials of dopamine reuptake transporters.
| Subject and group | Caudate nucleus left | Putamen left | Striatum left | Caudate nucleus right | Putamen right | Striatum right | Asymmetry index | STN– |
|---|---|---|---|---|---|---|---|---|
| wue03 | 0.49 | 0.31 | 0.40 | 0.31 | 0.28 | 0.30 | 28.57 | R |
| wue09 | 0.72 | 0.48 | 0.61 | 0.62 | 0.37 | 0.49 | 21.82 | R |
| wue04 | 1.15 | 0.70 | 0.93 | 0.58 | 0.44 | 0.50 | 60.14 | R |
| wue02 | 0.88 | 0.57 | 0.72 | 1.43 | 0.91 | 1.17 | 47.62 | L |
| wue10 | 0.97 | 0.50 | 0.75 | 1.20 | 0.74 | 0.96 | 24.56 | L |
| wue07 | 0.92 | 0.64 | 0.76 | 1.22 | 0.79 | 1.00 | 27.27 | L |
| wue06 | 1.31 | 0.59 | 0.95 | 1.56 | 0.91 | 1.20 | 23.26 | L |
| wue11 | 1.15 | 0.79 | 0.96 | 1.41 | 0.74 | 1.05 | 8.96 | L |
| PD | 0.95±0.26* | 0.57±0.15* | 0.76±0.19* | 1.04±0.47* | 0.65±0.25* | 0.83±0.35* | 30.27±16.09* | |
| HC | 2.57±0.57 | 2.30±0.42 | 2.33±0.48 | 2.62±0.52 | 2.23±0.48 | 2.30±0.48 | 2.57±2.14 |
The BPND of DAT in the striatum was used to identify the hemisphere with less (i.e. STN–, bold) or more (i.e. STN+) dopaminergic innervation. For healthy subjects, we considered the average striatal binding of left and right, which did not significantly differ. Data are shown as mean ± standard deviation.
* p<0.05
Steel-Dwass all pairs. BPND, non-displaceable binding potential; DAT, dopamine reuptake transporter; HC = healthy control group; PD = Parkinson’s disease patient group; STN = subthalamic nucleus.