Table 1.
Reported dosimetry for endoscopic GI cryotherapy
| Indication | Number of cycles | Time per cycle (seconds) | Study reference |
|---|---|---|---|
| Liquid nitrogen cryotherapy | |||
| Barrett’s esophagus with dysplasia/IMCA | 2 | 20 | 22, 23 |
| Palliation of esophageal cancer | 3 | 20 | 33 |
| GAVE | 1 | HFA | 36 |
| Radiation proctopathy | 4 | 10 | 38 |
| Carbon dioxide cryotherapy | |||
| Barrett’s esophagus with dysplasia/IMCA | 5-7 | 15-30 | 25, 26 |
| Palliation of esophageal cancer | NDA | NDA | NDA |
| GAVE | 1 | HFA | 37 |
| Radiation proctopathy | NDA | NDA | NDA |
| Nitrous oxide cryotherapy | |||
| Barrett’s esophagus with dysplasia | 1 | 6-10 | 31 |
| Palliation of esophageal cancer | NDA | NDA | NDA |
| GAVE | NDA | NDA | NDA |
| Radiation proctopathy | NDA | NDA | NDA |
GAVE, Gastric antral vascular ectasia; HFA, cryogen applied until a hard freeze was achieved; IMCA, intramucosal carcinoma; NDA, no data available.