Table 6.
Secondary Outcome Measures at Baseline and 1, 6, and 12 mo Following PFO Closure
| Measure | Baseline | 1 mo | 6 mo | 12 mo | P Value |
|---|---|---|---|---|---|
| PaO 2, kPa | 11.2 (0.7) | 11.8 (0.5) | 10.7 (0.7) | 10.8 (1.5) | .23 |
| PaCO 2, kPa | 5.6 (4.5–5.8) | 5.6 (5.0–5.8) | 5.6 (5.3–6.1) | 5.5 (4.7–6.1) | .74 |
| AHI, events/h | 67.2 (24.9) | 67.7 (21.9) | 66.6 (31.0) | 68.5 (31.0) | .99 |
| ODI/AHI | 0.73 (0.34–0.87) | 0.73 (0.53–0.87) | 0.70 (0.44–0.90) | 0.85 (0.40–1.01) | .28 |
| BMI, kg/m2 | 33.7 (3.5) | 32.8 (3.5) | 34.3 (3.2) | 33.2 (3.4) | .06 |
| 6MWT distance, m | 558 (102) | 578 (81) | 584 (69) | 593 (79) | .17 |
| Epworth Sleepiness Score | 13 (3) | 11 (4) | 10 (5) | 11 (5) | .14 |
| HIT6 | 42 (40–59) | 43 (36–46) | 37 (36–52) | 41 (38–65) | .28 |
| SF-36v2: physical component | 47 (9) | 48 (7) | 52 (7) | 46 (9) | .08 |
| SF-36v2: mental health component | 51 (5) | 52 (4) | 47 (8) | 49 (7) | .43 |