Table 1.
Subject characteristics
| Characteristic | TD subjects | ASD subjects | P-value |
|---|---|---|---|
| N | 41 | 41 | |
| Gender | 34 male | 37 male | |
| Handedness | 38 right-handed | 36 right-handed | |
| Age (years) | 13.11 (1.8) | 13.52 (2.2) | 0.36 |
| Full-scale IQ | 106.12 (10.2) | 104.54 (14.4) | 0.57 |
| Verbal IQ | 106.59 (11.0) | 103.24 (13.3) | 0.22 |
| Performance IQ | 105.51 (11.1) | 105.12 (14.4) | 0.89 |
| ADOS (comm+ soc) | 11.85 (4.63) | ||
| ADI (comm) total | 16.29 (4.41) | ||
| Mean absolute motion | 0.25 (0.16) | 0.26 (0.14) | 0.72 |
| Max absolute motion | 0.75 (0.60) | 0.78 (0.45) | 0.84 |
| Mean framewise displacement | 0.06 (0.03) | 0.07 (0.03) | 0.22 |
| Max framewise displacement | 0.56 (0.62) | 0.54 (0.42) | 0.83 |
| Self-reported ethnicity/race | |||
| Asian | 1 | 2 | |
| Black or African American | 2 | 5 | |
| Hispanic/White | 13 | 12 | |
| Non-Hispanic/White | 18 | 16 | |
| Other/mixed | 7 | 6 | |
| Total OXTR risk alleles | 2.95 (1.05) | 3.26 (0.98) | 0.16 |
| Subjects (N) with ⩾ 1 risk allele | |||
| OXTR rs1042778 | 28 | 33 | |
| OXTR rs2254298 | 10 | 8 | |
| OXTR rs53576 | 15 | 23 | |
| OXTR rs237887 | 34 | 32 |
Abbreviations: ADI, Autism Diagnostic Interview; ADOS, Autism Diagnostic Observation Schedule; ASD, autism spectrum disorders; comm, communication; IQ, intelligence quotient; max, maximum; OXTR, oxytocin receptor gene; soc, social; TD, typically developing. Mean (s.d.). Subjects’ characteristics were matched across TD and ASD diagnostic groups.