Table 2.
Characteristics of Patient Hospitalization
| Variable | AKIN 0 (n = 5,663 [45.7%]) | AKIN 1 (n = 4,589 [37.0%]) | AKIN 2 (n = 1,613 [13.0%]) | AKIN 3 (n = 534 [4.3%]) | P Value |
|---|---|---|---|---|---|
| Diagnosis | |||||
| Postsurgery trauma | 1,360 (24.0) | 1,053 (22.9) | 432 (26.8) | 126 (23.6) | .02 |
| Sepsis | 282 (5.0) | 556 (12.1) | 292 (18.1) | 192 (36.0) | < .001 |
| Congestive heart failure | 977 (17.3) | 1,392 (30.3) | 523 (32.4) | 216 (40.4) | < .001 |
| Cirrhosis | 75 (1.3) | 108 (2.4) | 45 (2.8) | 24 (4.5) | < .001 |
| Pneumonia | 383 (6.8) | 750 (16.3) | 329 (20.4) | 157 (29.4) | < .001 |
| COPD | 503 (8.9) | 535 (11.7) | 180 (11.2) | 74 (13.9) | < .001 |
| GI bleeding | 311 (5.5) | 263 (5.7) | 88 (5.5) | 47 (8.8) | .02 |
| Diabetic ketoacidosis | 40 (0.7) | 69 (1.5) | 39 (2.4) | 17 (3.2) | < .001 |
| Neurologic event | 182 (3.2) | 180 (3.9) | 54 (3.3) | 8 (1.5) | .02 |
| Coronary artery disease | 2,304 (40.7) | 2,093 (45.6) | 663 (41.1) | 153 (28.7) | < .001 |
| ARDS | 84 (1.5) | 303 (6.6) | 177 (11.0) | 61 (11.4) | < .001 |
| RRT during admission | 0 (0.0) | 0 (0.0) | 0 (0.0) | 179 (33.5) | < .001 |
| Acuity score on admission | |||||
| SOFA | 4.27 ± 3.25 | 6.57 ± 3.58 | 7.66 ± 3.62 | 8.91 ± 4.19 | < .001a |
| SAPS I | 11.76 ± 4.79 | 14.72 ± 4.77 | 15.83 ± 4.75 | 16.36 ± 5.42 | < .001b |
| Treatment | |||||
| Mechanical ventilation | 2,647 (46.7) | 3,202 (69.8) | 1,267 (78.5) | 377 (70.6) | < .001 |
| Vasopressors | 1,613 (28.5) | 2,197 (47.9) | 923 (57.2) | 293 (54.9) | < .001 |
| Creatinine level | |||||
| Admission | 0.83 ± 0.33 | 1.10 ± 0.70 | 1.15 ± 0.83 | 2.71 ± 2.22 | < .001c |
| Maximum | 0.87 ± 0.34 | 1.29 ± 0.78 | 1.43 ± 0.94 | 3.99 ± 2.79 | < .001a |
| Discharge | 0.82 ± 0.32 | 1.05 ± 0.64 | 1.00 ± 0.62 | 2.47 ± 2.40 | < .001a |
| Mortality | |||||
| 1 y | 427 (7.6) | 540 (11.9) | 226 (14.1) | 120 (22.7) | < .001d |
| 2 y | 743 (13.1) | 875 (19.1) | 340 (21.1) | 171 (32.0) | < .001d |
Data are presented as No. (%) or mean ± SD. RRT = renal replacement therapy; SAPS I = Simplified Acute Physiology Score I; SOFA = Sequential Organ Failure Assessment. See Table 1 legend for expansion of other abbreviation.
a
Among all groups.
b
Between all groups other than 2 and 3.
c
Between all groups other than 2 and 1.
d
Kaplan-Meier mortality rates.