Table 1. Differential bone marrow cell count of Gfi1 mice kept under SPF and SPF+nonSPF conditions.
| SPF conditions | SPF+nonSPF conditions | SPF vs. SPF+nonSPF | |||||||
|---|---|---|---|---|---|---|---|---|---|
| value | unit | control | Gfi1 hom | t-test | control | Gfi1 hom | t-test | t-test controls | t-test Gfi1 hom |
| n | 4 | 3 | 3 | 4 | |||||
| neutrophile promyelocytes | % | 1.75 ± 0.66 | 4.90 ± 1.14 | p ≤ 0.01 | 2.63 ± 0.75 | 5.18 ± 1.32 | p ≤ 0.05 | n.s. | n.s. |
| neutrophile myelo- and metamyelocytes | % | 14.63 ± 4.97 | 0.07 ± 0.06 | p ≤ 0.01 | 17.70 ± 11.79 | 0.43 ± 0.46 | p ≤ 0.05 | n.s. | n.s. |
| neutrophile granulocytes | % | 7.33 ± 0.97 | 0.00 ± 0.00 | p ≤ 0.01 | 9.80 ± 6.77 | 0.00 ± 0.00 | p ≤ 0.05 | n.s. | n.s. |
| eosinophile promyelocytes | % | 0.30 ± 0.08 | 0.57 ± 0.31 | n.s. | 0.30 ± 0.10 | 0.40 ± 0.08 | n.s. | n.s. | n.s. |
| eosinophile myelo- and metamyelocytes | % | 2.28 ± 0.53 | 3.83 ± 1.47 | n.s. | 1.83 ± 0.78 | 2.45 ± 0.76 | n.s. | n.s. | n.s. |
| eosinophile granulocytes | % | 0.83 ± 0.26 | 0.40 ± 0.20 | n.s. | 0.90 ± 0.62 | 0.43 ± 0.39 | n.s. | n.s. | n.s. |
| lymphocytes | % | 6.40 ± 3.57 | 4.87 ± 1.07 | n.s. | 7.63 ± 2.15 | 2.25 ± 0.95 | p ≤ 0.01 | n.s. | p ≤ 0.05 |
| monocytes | % | 0.53 ± 0.17 | 0.70 ± 0.44 | n.s. | 0.47 ± 0.25 | 0.88 ± 0.46 | n.s. | n.s. | n.s. |
| erythrocytes | % | 65.15 ± 4.41 | 36.47 ± 8.38 | p ≤ 0.01 | 58.23 ± 18.92 | 27.53 ± 4.76 | p ≤ 0.05 | n.s. | n.s. |
| atypical myeloid cells (ring nucleus) | % | 0.00 ± 0.00 | 1.73 ± 1.16 | p ≤ 0.05 | 0.00 ± 0.00 | 1.83 ± 0.81 | p ≤ 0.05 | n.s. | n.s. |
| atypical myeloid cells (others) | % | 0.00 ± 0.00 | 45.63 ± 6.37 | p ≤ 0.01 | 0.00 ± 0.00 | 56.83 ± 5.24 | p ≤ 0.01 | n.s. | n.s. |
| other blasts | % | 0.83 ± 0.71 | 0.83 ± 0.06 | n.s. | 0.50 ± 0.10 | 0.68 ± 0.44 | n.s. | n.s. | n.s. |
Statistical significance calculated by unpaired t-test of controls vs. Gfi1 hom. All values are given as mean ± standard deviation. n.s.—not significant.