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. 2018 Jun 7;13(6):e0198445. doi: 10.1371/journal.pone.0198445

Fig 5. The diagnostic performance of the biomarker module Mod_14 and its individual miRNAs or combinations based on the ROC curves.

Fig 5

A. ROC curves of Mod_14 and its individual miRNAs. Red line, Mod_14 (AUC = 0.838, sensitivity = 68.9%, specificity = 94.1%); Blue line, miR_486 (AUC = 0.747, sensitivity = 82.2%, specificity = 58.8%); Green line, miR_451 (AUC = 0.819, sensitivity = 72.2%, specificity = 91.2%); Orange line, miR_185 (AUC = 0.751, sensitivity = 76.7%, specificity = 67.6%); Greenyellow line, miR_600 (AUC = 0.487, sensitivity = 18.9%, specificity = 85.3%). B. ROC curves of miRNA combinations in Mod_14. Red line, combination of miR_451 and miR_185 (AUC = 0.904, sensitivity = 81.1%, specificity = 97.1%); Blue line, combination of miR_451, miR_486 and miR_185 (AUC = 0.838, sensitivity = 67.8%, specificity = 94.1%); Green line, combination of miR_451 and miR_486 (AUC = 0.550, sensitivity = 85.6%, specificity = 26.5%); Orange line, combination of miR_486 and miR_185 (AUC = 0.811, sensitivity = 68.9%, specificity = 91.2%).