TABLE 1.

PICOTS Elements Table With Inclusion and Exclusion Criteria

Study Characteristic	Inclusion Criteria	Exclusion Criteria
Populations	• Humans	None
	• Patients with cough (any duration)
Interventions	• Qualitative and quantitative instruments used to assess cough (eg, general and cough-specific health-related quality of life instruments, visual analog scales, objective cough counting, tussigenic challenge, exhaled nitric oxide)	None
Comparators	•Other instruments •Cough counts as reference standard for cough frequency instruments	None
Outcomes	• Study assesses an outcome of interest:	None
	∘ Diagnostic accuracy (eg, sensitivity, specificity, positive predictive value, negative predictive value, validity, reliability, responsiveness, feasibility)
	∘ Therapeutic efficacy (eg, change in clinical practice, impact on patient or provider decision-making)
	∘ Patient outcome efficacy (eg, acceptability, quality of life, chest pain, depression, anxiety)
Timing	• Timing of follow-up not limited	None
Setting	• Inpatient and outpatient	None
Study design	• Evaluation studies	• Not a clinical study (eg, editorial, nonsystematic review, letter to the editor, case series)
Publications	•English-language only •Peer-reviewed articles •Relevant systematic review, meta-analysis, or methods article (used only for background and as potential sources of additional relevant material)	• Non-English-language publications

PICOTS = population of interest, interventions, comparators, outcomes, timing of outcomes, and settings.