Table 1.
Three-way ANOVA analysis of brain structure, MeHg and sex on antioxidant response in young mice.
| Factor | TrxR cytoplasmic extracts |
TrxR nuclear extracts |
TrxR1 mRNA |
Trx cytoplasmic extracts |
Trx nuclear extracts |
Trx1 mRNA |
GPx cytoplasmic extracts |
GPx1 mRNA |
GSH cytoplasmic extracts |
|---|---|---|---|---|---|---|---|---|---|
| brain structure | F = 95.329 | F = 78.178 | F = 10.092 | F = 0.968 | F = 189.337 | F = 101.764 | F = 2.213 | F = 23.484 | F = 0.865 |
| p <0.001 | p <0.001 | p = 0.003 | p = 0.332 | p <0.001 | p <0.001 | p = 0.146 | p <0.001 | p = 0.359 | |
| MeHg | F = 12.579 | F = 13.427 | F = 5.222 | F = 0.041 | F = 0.175 | F = 3.242 | F = 0.264 | F = 1.568 | F = 3.684 |
| p = 0.001 | p = 0.01 | p = 0.029 | p = 0.841 | p = 0.678 | p = 0.081 | p = 0.611 | p = 0.219 | p = 0.063 | |
| sex | F = 1.146 | F = 25.071 | F = 0.449 | F = 7.487 | F = 2.053 | F = 7.325 | F = 0.912 | F = 9.255 | F = 1.549 |
| p = 0.292 | p <0.001 | p = 0.507 | p = 0.01 | p = 0.161 | p = 0.011 | p = 0.346 | p = 0.004 | p = 0.221 | |
| brain structure × MeHg | F = 0.692 | F = 1.534 | F = 2.194 | F = 0.337 | F = 1.616 | F = 7.498 | F = 0.22 | F = 1.041 | F = 0.128 |
| p = 0.411 | p = 0.224 | p = 0.148 | p = 0.565 | p = 0.212 | p = 0.01 | p = 0.884 | p = 0.300 | p = 0.723 | |
| brain structure × sex | F = 25.481 | F = 4.402 | F = 21.848 | F = 7.849 | F = 1.584 | F = 4.971 | F = 0.176 | F = 13.324 | F = 1.262 |
| p <0.001 | p = 0.043 | p <0.001 | p = 0.008 | p = 0.216 | p = 0.033 | p = 0.677 | p = 0.001 | p = 0.268 | |
| sex × MeHg | F = 44.809 | F = 27.147 | F = 2.905 | F = 0.222 | F = 0.340 | F = 64.361 | F = 8.575 | F = 1.029 | F = 3.515 |
| p <0.001 | p <0.001 | p = 0.097 | p = 0.641 | p = 0.563 | p <0.001 | p = 0.006 | p = 0.317 | p = 0.069 | |
| brain structure × sex × MeHg | F = 6.459 | F = 7.622 | F = 0.317 | F = 0.556 | F = 0.049 | F = 35.53 | F = 0.121 | F = 0.351 | F = 2.451 |
| p = 0.015 | p = 0.009 | p = 0.577 | p = 0.461 | p = 0.825 | p <0.001 | p = 0.730 | p = 0.557 | p = 0.126 |