Table 3.

Significant spatiotemporal clusters of NTD-related deaths excluding Chagas disease, defined using space-time scan statistics by municipality of residence, Brazil, 2000–2011.

Cluster	Time period	Number of municipalities	States	Region	Radius (km)	Number of deaths	Expected number of deaths	Annual mortality ratea	RR	LLR	p-Value
1	2001–2006	181	Paraíba, Pernambuco and Sergipe	Northeast	173.1	2509	656.1	4.9	4.10	1.576.51	< 0.001
2	2006–2011	884	Pará, Tocantins, Maranhão, Piauí, Ceará, Rio Grande do Norte, Paraíba, Pernambuco and Bahia	North and Northeast	681.9	2892	1812.4	2.0	1.66	294.24	< 0.001
3	2007–2011	395	Rondônia, Mato Grosso, Mato Grosso do Sul, Tocantins, Goiás, Minas Gerais and São Paulo	North, Central-west and Southeast	769.2	1190	598.7	2.5	2.03	232.53	< 0.001
4	2006–2011	596	Bahia, Goiás, Minas Gerais and Espírito Santo	Northeast, Southeast and Central-west	432.8	1849	1213.8	1.9	1.56	150.55	< 0.001
5	2000–2005	1	São Paulo	Southeast	0.0	94	11.0	10.9	8.57	118.75	< 0.001
6	2008–2008	11	Rio de Janeiro	Southeast	34.4	320	122.7	3.3	2.63	110.21	< 0.001
7	2010–2010	8	São Paulo	Southeast	39.3	85	20.7	5.2	4.11	55.67	< 0.001
8	2000–2004	1	Paraná	South	0.0	33	5.2	8.1	6.31	32.99	< 0.001
9	2000–2004	1	Minas Gerais	Southeast	0.0	26	4.3	7.8	6.06	25.12	< 0.001
10	2001–2006	1	Santa Catarina	South	0.0	9	0.3	40.1	31.36	22.30	< 0.001
11	2010–2010	4	São Paulo	Southeast	11.8	10	0.6	20.9	16.31	18.53	0.002
12	2001–2004	1	São Paulo	Southeast	0.0	48	17.7	3.5	2.72	17.64	0.005

RR: relative risk for the cluster compared with the rest of the country; LLR: log likelihood ratio.

^aNTD-related mortality rates (per 100,000 inhabitants) during the clustering time.