Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hyperactivation of PKR in Non-tumorigenic Human Cells Following Infection with D9- or D10-Deficient VACV
Human HCC (HepG2, Hep3B, and Huh7) or untransformed, non-tumorigenic cBAL111 human liver cells were either mock-infected or infected (MOI = 5) with WT VACV, D9-deficient VACV (ΔD9), or D10-deficient VACV (ΔD10). After 18.5 hr, total protein was isolated and analyzed by immunoblotting with either total PKR or a PKR phospho-specific antibody as described.36
