Tornado diagram showing the 10 most sensitive model parameters in MELD 20, i.e. the cutoff score to accept HCV-positive liver, and in MELD 28, i.e. the MELD score with the highest gain in life years. In both cases, HCV-positive organ rate had the highest impact on the primary model outcome, i.e. change in life years.
*Parameters having a value by each MELD score. Basically, we used +/− 25% change from baseline values
**Post-LT corresponds to Post-LT (Non-viremic) and Post-LT (SVR) stages in the model.
***Post-LT Viremic correspond to stages including salvage therapy, F0–F2, and F3–F4 in HCV-positive arm in the model
Abbreviations: HCV, hepatitis C virus; LT, liver transplant; SVR, sustained virologic response; GR, graft failure; TP, transition probability