Table 3.

Association between past false-positives on cancer screening tests and future receipt of cancer screenings^*

	Females								Males
	Up-to-date with colorectal cancer screening				Up-to-date with breast cancer screening				Up-to-date with colorectal cancer screening
Column	(1)		(2)		(3)		(4)		(5)		(6)
	Unadjusted		Adjusted		Unadjusted		Adjusted		Unadjusted		Adjusted
	OR (95% CI)	P	AOR (95% CI)	P	OR (95% CI)	P	AOR (95% CI)	P	OR (95% CI)	P	AOR (95% CI)	P
Ever had false-positive breast cancer screening
Repeat breast imaging within 91 d (no biopsy)	1.35 (1.30–1.39)	<0.001	1.25 (1.18–1.32)	<0.001	2.42 (2.29–2.56)	<0.001	1.43 (1.34–1.51)	<0.001
Breast biopsy	1.50 (1.32–1.70)	<0.001	1.47 (1.23–1.77)	<0.001	3.25 (2.52–4.19)	<0.001	2.02 (1.56–2.62)	<0.001
Ever had false-positive colorectal cancer screening†
Positive FOBT with negative follow-up colonoscopy within 6 m, without biopsy/polypectomy†					0.97 (0.81–1.15)	0.69	0.73 (0.61–0.81)	<0.001
Ever had false-positive prostate cancer screening
PSA ≥4.0 ng/mL (repeated within 91 d, no imaging/biopsy)									1.42 (1.27–1.58)	<0.001	1.22 (1.01–1.48)	0.039
Prostate imaging/ biopsy									1.87 (1.43–2.45)	<0.001	1.60 (1.05–2.42)	0.028
Receipt of prior cancer screening
Up-to-date with breast cancer screening (past 2 y)			1.78 (1.68–1.90)	<0.001
Up-to-date with colorectal cancer screening‡							1.81 (1.69–1.93)	<0.001
Had prostate cancer screening (past 2 y)											1.34 (1.27–1.42)	<0.001
Psuedo-R2	0.03		0.51		0.29		0.41		0.02		0.53
N person-years	262,242		262,242		262,242		262,242		188,242		188,242
N individuals	52,871		52,871		52,871		52,871		39,534		39,534

^*Adjusted models controlled for covariates as described in manuscript.

^†We did not consider false-positives for patients who underwent initial colonoscopy because repeat screening would not be expected during the study period.

^‡Receipt of FOBT within 1 year, flexible sigmoidoscopy within 5 years or colonoscopy within 10 years.