Figure 1.
A. A typical well differentiated (WD) G2 neoplasm with round nuclei and smooth contours B. G2 neoplasm with abundant cytoplasm and nuclear tangles. C-E. Three poorly differentiated neuroendocrine carcinomas, large cell type on Thinprep (C), cell block (D), and Diff Quik preparations (E). F-G. Two poorly differentiated neuroendocrine carcinomas, small cell type on Thinprep (F) and Diff Quik (G) preparations. H-I. Poorly differentiated neuroendocrine carcinomas, not otherwise specified. KRAS, TP53, and RB1 mutations were detected in the neoplasm in Figure 1I.