Table 2.

Hematologic and Organ response with treatment in patients with newly diagnosed AL

	CPCs Present N=60 N (%)	CPCs Absent N=89 N (%)	P value
Hematologic Response
Evaluable	N=36	N=67
Complete Response	12 (33)	26 (39)
VGPR	11 (31)	18 (27)
Partial Response	8 (22)	15 (22)
No response/progression	5 (14)	8 (12)
VGPR or better rate	23 (64)	44 (65)	0.9*
Not evaluable	9	16
Not known/died before assessment	15	6
Organ Response
Cardiac response, n/N (%)	9/19 (47)	20/35 (57)	0.5
Renal response, n/N (%)	20/25 (80)	35/48 (73)	0.5
Liver response, n/N (%)	4/4 (100)	1/7 (14)	0.002
Median time to cardiac response, months (IQR)	9 (4-17)	9 (5-13)	1
Median time to renal response, months (IQR)	7 (3-14)	6 (3-12)	0.8
Median time to liver response, months (IQR)	4 (3-8)	4 (4-4)	1

^*p value for comparison of VGPR or better response

Abbreviations: VGPR: very good partial response; IQR: interquartile range