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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Mov Disord. 2018 Mar 23;33(5):793–804. doi: 10.1002/mds.27326

Table 2.

Comparison of levels of immune and angiogenesis factors in stool from PD patients and controls

PATIENTS CONTROLS

Panel Factor N Mean
(pg/mg)
Std Dev N Mean
(pg/mg)
Std Dev p-value
Angiogenesis Flt1 156 5.020 4.272 110 3.957 3.059 0.0184
PlGF 156 1.439 1.132 110 1.352 0.6687 0.4328
Tie2 156 194.2 152.1 110 181.3 103.7 0.4112
VEGF-C 156 117.3 108.9 110 116.7 124.4 0.9662
VEGF-D 156 19.49 14.50 110 19.39 11.32 0.9489
bFGF 156 0.6937 0.5598 110 0.6165 0.4322 0.2040

Chemokine Eotaxin 156 8.878 6.160 110 8.113 5.119 0.2697
Eotaxin-3 156 24.05 19.06 110 22.35 20.77 0.4877
IP-10 156 0.4657 0.4559 110 0.3964 0.2818 0.1265
MCP-1 156 0.3225 0.5859 110 0.2562 0.2816 0.2195
MCP-4 156 4.759 3.468 110 4.214 2.508 0.1366
MDC 156 11.56 8.549 110 11.48 6.903 0.9306
MIP-1α 156 4.879 4.204 110 4.363 3.370 0.2673
MIP-1β 156 2.459 2.063 110 2.236 1.832 0.3616
TARC 156 0.7362 0.6579 110 0.7790 0.5600 0.5781

Cytokine IL-12/23 p40 156 2.634 1.779 110 2.481 1.522 0.4610
IL-15 156 0.8354 0.6445 110 0.7519 0.6075 0.2857
IL-16 156 16.34 17.50 110 15.28 14.17 0.5848
IL-17A 156 2.955 8.555 110 2.104 1.452 0.2231
IL-1α 156 98.99 326.8 110 41.65 40.39 0.0311
IL-5 156 0.7553 0.8279 110 0.7062 0.6693 0.5926
IL-7 156 0.7442 0.6159 110 0.6886 0.4264 0.3829
LTA 155 0.4188 0.4499 110 0.4174 0.3734 0.9778
VEGF 155 22.36 82.51 110 14.48 52.62 0.3423

Proinflammatory IFNγ 155 11.93 27.88 110 9.68 14.49 0.3906
IL-10 155 2.231 5.473 110 1.745 2.900 0.3487
IL-13 155 3.463 2.437 110 3.255 1.880 0.4305
IL-1β 155 3.451 12.22 110 1.685 2.486 0.0810
IL-2 155 3.161 3.922 110 2.815 2.312 0.3664
IL-4 155 0.6397 0.7944 110 0.5895 0.7576 0.6042
IL-6 155 3.024 6.367 110 2.660 4.818 0.5951
IL-8 155 41.5 149.1 110 14.0 53.5 0.0358
TNF 155 0.7482 1.055 110 0.7787 0.9975 0.8121

Vascular Injury CRP 155 1010 2909 110 547.4 1605 0.0978
SAA 155 109.1 378.7 110 71.76 53.12 0.2257
sICAM-1 155 19.87 44.79 110 13.22 41.83 0.2202
sVCAM-1 155 22.26 22.09 110 22.61 21.50 0.8953

Mean protein levels (pg/mg total protein) with standard deviations (Std Dev) in stool homogenates

N = number of measurements for each subject group

Gray shading indicates significant (p<0.05) difference between patients and controls by t-test