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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Stem Cells. 2018 Mar 1;36(6):881–890. doi: 10.1002/stem.2804

Figure 6. The CXCR4/CXCL12 pathway is involved in lesion expansion and proliferation.

Figure 6

Immunofluorescence Analysis of ectopic lesions in endometriosis induced mice. A: To investigate the contribution of CXCR4 positive ectopic endometrial-derived stem cells to the expansion of ectopic lesion, DsRed(A-1,B-1), CXCR4 (A-2,B-2), CD140B (A-3), and CD146(B-3) were used to mark mesenchymal stem cells that give rise to blood vessels within a lesion and lesion expansion. B: CXCR4 positive new blood vessels (yellow arrow) and single cells expressing mesenchymal stem cell markers (blue arrows) were found in recipient peritoneal wall. Scale bars = 20µM.