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A) body habitus, hypo- and hyper-pigmented patches as well as acanthosis nigricans and striae on abdomen, back, shoulders, and legs; B) ridged and peeling fingernails; C) thickened toenails, pes planus, and hallux valgus deformity; D) telomere length in total lymphocytes measured by flow cytometry with in situ hybridization
