. Author manuscript; available in PMC: 2019 Jun 1.

Published in final edited form as: Aliment Pharmacol Ther. 2018 Apr 17;47(11):1472–1479. doi: 10.1111/apt.14665

Table 2.

Multivariate Cox proportional hazard analysis examining factors associated with treatment failure in biologic-treated patients with ulcerative colitis

Variables	Hazard ratio	95% CI	p-value
Body mass index (per 1kg/m² increase)	1.043	1.004-1.082	0.029
Prior prednisone use (yes vs. no)	1.852	0.93-3.67	0.078
Concomitant immunomodulators (yes vs. no)	0.652	0.415-1.024	0.063
Albumin (<3.5g/dl vs. ≥3.5g/dl)	1.733	1.028-2.924	0.045
Disease duration (per 1y)	0.951	0.912-0.991	0.018
Prior anti-TNF failure (yes vs. no)	0.753	0.463-1.223	0.25

[Abbreviations: CI=confidence interval, TNF=tumour necrosis factor]