Table 3.
Multivariate Cox proportional hazard analysis examining factors associated with IBD-related surgery or hospitalization in biologic-treated patients with ulcerative colitis
Variables | Hazard ratio | 95% CI | p-value |
---|---|---|---|
Body mass index (per 1kg/m2 increase) | 1.078 | 1.020-1.138 | 0.008 |
Prior prednisone use (yes vs. no) | 1.894 | 0.559-6.419 | 0.305 |
Concomitant immunomodulators (yes vs. no) | 1.006 | 0.481-2.104 | 0.988 |
Albumin (<3.5g/dl vs. ≥3.5g/dl) | 1.318 | 0.548-3.165 | 0.537 |
Disease duration (per 1y) | 0.999 | 0.934-1.068 | 0.974 |
Prior anti-TNF failure (yes vs. no) | 0.675 | 0.290-1.571 | 0.362 |
Prior hospitalization (yes vs. no) | 2.261 | 1.012-5.053 | 0.047 |
[Abbreviations: CI=confidence interval, TNF=tumour necrosis factor]