Table 2.

Univariate analysis, 5-year Disease-Free Survival

Variables	N (%)	5-year DFS	95% CI	p-value
All patients	754 (51.1%)			-
Age				0.88
< 65 years	528 (70.4%)	79.6%	74.4–83.9
≥ 65 years	222 (29.6%)	80.8%	71.9–87.1
Gender				0.64
Male	375 (49.7%)	79.9%	73.8–84.8
Female	379 (50.3%)	78.9%	73.4–84.9
ASA Class				0.98
1–2	331 (46.0%)	80.2%	73.7–85.3
3–4	388 (54.0%)	79.2%	72.5–84.4
Functional Status				0.007
Non-functional	305 (40.8%)	87.6%	81.9–91.6
Functional	443 (59.2%)	73.7%	67.2–79.2
Genetic Syndrome				0.24
Not Associated	695 (93.0%)	61.1%	35.9–78.9
Associated	52 (7.0%)	67.2%	58.6–74.4
Multifocal				0.68
No	615 (93.6%)	79.9%	75.3–83.8
Yes	42 (6.4%)	76.6%	45.8–91.3
Primary				0.93
Gastriontestinal	265 (35.2%)	71.9%	61.5–80.0
Pancreas	489 (64.8%)	67.7%	44.8–74.8
Tumor Differentiation				<0.001
Well differentiated	562 (88.2%)	83.4%	78.6–87.2
Moderately differentiated	59 (9.3%)	65.2%	44.2–79.9
Poorly differentiated	16 (2.5%)	38.6%	13.4–63.6
Ki-67 Index Label				<0.001
<3%	282 (60.3%)	82.6%	71.5–89.7
3–20%	162 (34.6%)	69.7%	57.8–78.9
>20%	24 (5.1%)	26.6%	7.3–51.1
Lymph node Status				<0.001
Negative	368 (48.8%)	84.6%	79.2–87.1
1–3 Positives	156 (20.7%)	71.8%	64.7–78.2
>3 Positives	72 (9.5%)	56.9%	46.1–69.5
Tumor Size				<0.001
< 3 cm	521 (69.1%)	87.3%	82.5–90–8
≥ 3 cm	233 (30.9%)	66.3%	57.8–73.5
Final Margin Status				0.08
Negative	644 (85.9%)	80.8%	76.2–84.7
Positive	105 (14.0%)	73.9%	59.4–83.9
Lymph-vascular Invasion				<0.001
Absent	369 (66.3%)	89.4%	84.0–93.1
Present	188 (33.8%)	61.5%	50.9–70.6
Perineural Invasion				<0.001
Absent	366 (74.5%)	85.9%	80.1–90.2
Present	125 (25.5%)	62.1%	48.4–73.1