Fig. 6. Western blot analysis exhibiting levels of Cathepsin K and myofibrillar protein markers in myocardium from control and cardiac-specific Ctsk-CKO mice treated with or without doxorubicin.

a Representative gel blots depicting expressions of Cathepsin K, desmin, sarcomeric α-actinin, and GAPDH (loading control); b Cathepsin K/GAPDH; c Desmin/GAPDH; d Sarcomeric α-actinin/GAPDH. Mean ± SEM, n = 6–8 mice per group, *p < 0.05 vs. Control group, #p < 0.05 vs. Control-Dox group