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. 2018 Jun 7;8:8706. doi: 10.1038/s41598-018-26818-2

Table 1.

Summary of actin activated ATPase and in vitro motility results.

Construct V0 (s−1) kcat (s−1) KATPase (µM) KActin (µM) Velocity (nm/s)
MYO3A ΔK 2IQ WT 0.09 ± 0.01 2.19 ± 0.09 1.93 ± 0.48 4.69 ± 1.60 54.8 ± 0.6
MYO3A ΔK 2IQ  L697W 0.13 ± 0.01 0.31 ± 0.01 ≤0.77 2.21 ± 0.53 31.3 ± 0.4

ATPase data (represented as mean ± SEM) and in vitro motility data (represented as mean ± SEM; n = 150 filaments) were reported from at least 3 protein preparations.