Fig. 4.

Molecular structure, posttranslational modifications, and protein–protein interactions of the Ski and SnoN proteins. a, b The domains that define the Ski and SnoN proteins include: Dachshund homology domain (DHD), SAND-like domain, and coiled-coil domain (CC). Both the Ski and SnoN proteins are regulated by PTMs, as catalyzed by several enzymes at specific residues that are indicated. Known regions of interaction with some partners for Ski and SnoN are indicated. c Several proteins are also partners for Ski and/or SnoN but the interacting domains are not identified. Kinases are shown in green, transcriptional coregulators in blue, transcription factors in red, and other proteins in black