Table 3.
Variable | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Risk ratio | 95% CI | P | Risk ratio | 95% CI | P | |
Gender | 0.278 | 0.257–2.058 | 0.549 | |||
Male vs. female | ||||||
Age (years) | 1.029 | 0.995–1.064 | 0.090 | |||
≤65 vs. >65 | ||||||
Smoking history | 1.603 | 0.667–3.853 | 0.291 | |||
Smokers vs. never smokers | ||||||
Histological subtype | 1.338 | 0.518–3.453 | 0.547 | |||
SCC vs. ACC | ||||||
Adjacent organs invasion | 0.806 | 0.402–1.614 | 0.542 | |||
Negative vs. positive | ||||||
Tumor size (cm) | 1.017 | 0.881–1.174 | 0.821 | |||
≤5 vs. >5 | ||||||
Necrosis | 1.177 | 0.579–2.393 | 0.652 | |||
Negative vs. positive | ||||||
Lymph node metastasis | 3.311 | 1.665–6.583 | 0.001* | 1.802 | 0.684–4.746 | 0.233 |
Negative vs. positive | ||||||
TNM stage | 1.941 | 1.322–2.850 | 0.001* | 1.498 | 0.867–2.587 | 0.148 |
I+II vs. III+IV | ||||||
C9 expression of TAMs | 0.367 | 0.167–0.807 | 0.013* | 0.413 | 0.186–0916 | 0.029* |
High vs. low |
CI confidence interval, TAMs tumor-associated macrophages, SCC squamous cell carcinoma, ACC adenocarcinoma
*P < 0.05, overall