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. 2018 Jun 7;8:8717. doi: 10.1038/s41598-018-26100-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The ROC curves corresponding to the mean gist response calculated based on abnormality scores given by radiologists number 14 and 4 (the best and the second best readers). The red curve shows the classification performance when all cases in the Prior_Invis category were included and the blue curve shows the classification performance when ten cases in the Prior_Invis category with the highest abnormality scores were omitted. At this point the difference between the Prior_Invis and Normal categories is marginally significant.