Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 8;11:170–179. doi: 10.1016/j.omtn.2018.02.001

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Cryptotanshinone Regulates the Expression of miRNAs in Chondrocytes

(A) Venn diagram of microarray analysis comparison between control (yellow) and CTS (purple) group indicated that a total of 1,006 miRNAs were differentially expressed (brown). Ctrl, Control; CTS, Cryptotanshinone. (B) A volcano plot indicating differentially regulated miRNA expression. miRNAs upregulated and downregulated are shown in red and green, respectively. Values are presented as the log2 of tag counts. (C) Hierarchical clustering analysis of miRNAs in chondrocytes stimulated with CTS (10 μM). The level of miRNA expression is color coded: red, upregulation; blue, downregulation; white, no change. (D) qRT-PCR measurement of miRNAs upregulated in the microarray assays. (E) Cultured human chondrocytes stimulated with CTS at different times were analyzed for miR-106a-5p expression. Each bar represents the mean ± SD of at least three independent experiments performed in triplicate. *p < 0.05, **p < 0.01.