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. 2018 Feb 8;11:170–179. doi: 10.1016/j.omtn.2018.02.001

Figure 2.

Figure 2

miR-106a-5p Protects Mice from Developing OA

(A) Representative μCT images of coronal and sagittal views of the knee joints. Scale bar, 1 μm. (B) Quantitative analysis of surface covered area and cartilage volume in mice (n = 6). (C) H&E, Safranin O/fast green staining (S/F), and Masson trichrome staining were performed to examine the proteoglycan content in the cartilage. Scale bar, 200 μm. (D) OARSI grades of the mice are shown (n = 6); yellow, sham; red, control; yellow, miR-106a-5p. (E) Time of mice on rotarod 8 weeks after an anterior cruciate ligament transection (ACLT) (n = 6); yellow, sham; red, control; yellow, miR-106a-5p. Each bar represents the mean ± SD. *p < 0.05, **p < 0.01.