Table 3.
Cross-sectional studies of the white cell count in type 2 diabetes.
| Reference | Groups | Endpoint | Findings | p Value |
|---|---|---|---|---|
| Ohshita et al. (55) | Impaired glucose tolerance (n = 476) vs impaired fasting glucose (n = 290) | Mean white cell count | 6,530 vs 6,210/mm3 | p < 0.05 |
| Chung et al. (53) | Normoalbuminuria (n = 888) vs microalbuminuria (n = 326) vs overt nephropathy (n = 266) | Mean white cell count | 6,572 ± 1,647 vs 6,984 ± 1,662 vs 7,440 ± 1,769 × 109/la | p < 0.0001 |
| Normoalbuminuria (n = 888) vs microalbuminuria (n = 326) vs overt nephropathy (n = 266) | Mean neutrophil count | 3,730 ± 1,283 vs 4,101 ± 1,432 vs 4,742 ± 1,590 × 109/la | p < 0.0001 | |
| Normoalbuminuria (n = 888) vs microalbuminuria (n = 326) vs overt nephropathy (n = 266) | Mean lymphocyte count | 2,222 ± 736 vs 2,206 ± 701 vs 1,937 ± 769 × 109/la | p < 0.001 | |
| Normoalbuminuria (n = 888) vs microalbuminuria (n = 326) vs overt nephropathy (n = 266) | Mean monocyte count | 440 ± 158 vs 482 ± 173 vs 553 ± 237 × 109/la | p < 0.0001 | |
| Cavalot et al. (54) | Microalbuminuria (n = 140) vs normoalbuminuria (n = 476) | Mean white cell count | 7,539 ± 1,882 vs 6,882 ± 1,713 μ/la | p = 0.0051 |
| Macroalbuminuria (n = 43) vs normoalbuminuria (n = 476) | Mean white cell count | 7,574 ± 1,981 vs 6,882 ± 1,713 μ/la | p = 0.0143 | |
aSD.