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. 2018 May 29;8:192. doi: 10.3389/fonc.2018.00192

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Copyright © 2018 Durante and Formenti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Collection of measured relative biological effectiveness (RBE) data for the induction of MN per BN cell after exposure to protons, α-particles, or energetic heavy ions. RBE was calculated as the ratio of the initial slope of the dose-response curves for ions and photons as measured by the same authors. Different symbols refer to different cell types. HaCaT = spontaneously immortalized adult human keratinocytes (63); NHPK = normal human neonatal epidermal keratinocytes (63); HUVEC = human umbilical vein endothelial cells (67); HNDF = human neonatal dermal fibroblasts (59); FRTL-5 = Fischer rat thyroid cell line (60); PBL = human peripheral blood lymphocytes (61); SCCVIII = mouse squamous cell carcinoma (64); V79 =Chinese hamster fibroblasts (62); Cl-1 = Chinese hamster fibroblasts (46). The blue line is a guide for the eye.