Figure 4.

NK cell co-culture reduces migration and invasion capacities of oxaliplatin-resistant colorectal cancer cell lines. A and B. Oxaliplatin-resistant (OR)-DLD1 and OR-RKO cells were injected into mice (n=8 each group), without (NK cell -) or with co-injection of natural killer cells (NK cell +), respectively, followed by growth curve evaluation on day 7, 14 and 21 after injection. C and D. At the end of day 21, xenograft tumors from all mice were extracted and weighed. Data are presented as mean ± SD, n=8 each group. **P<0.01, *P<0.05, NK cell - vs NK cell +.