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. 2018 May 1;8(5):824–834.

Figure 5.

Figure 5

NK cell co-culture reduces WBSCR22 expression in oxaliplatin-resistant colorectal cancer cell lines. A. Oxaliplatin-resistant (OR)-DLD1 and OR-RKO cells in the absence (NK cell -) or presence (NK cell +) of co-cultured natural killer cells, respectively, were subjected to RT-PCR and Western blot analyses to assess mRNA and protein levels of WBSCR22. Data are presented as mean ± SD from at least three independent experiments. B. At the end of day 21, OR-DLD1 and OR-RKO xenograft tumors from all mice were extracted and subjected to RT-PCR and Western blot analyses to assess mRNA and protein levels of WBSCR22. Data are presented as mean ± SD, n=8 each group. **P<0.01, *P<0.05, NK cell - vs NK cell +.