Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 1;10:164. doi: 10.3389/fnagi.2018.00164

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Huang, Liang, Chen, Xu, Chai and Xing.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Fluoxetine protection of synapses in 3×Tg-AD neurons. (A) Double-labeling analysis results for neurons from WT mice, 3×Tg-AD, and fluoxetine-treated 3×Tg-AD mice. Neuronal marker MAP2 (red) with post synaptic density protein 95 (PSD95) (green). Scale bar = 100 μm. (B) The levels of Syna and PSD95 expression were analyzed via Western blot assay. WT, primarily cultured neurons of wild-type mice; Tg, primarily cultured neurons of 3×Tg-AD mice; Tg + FLX, primarily neurons of 3×Tg-AD mice treated with fluoxetine. Data were shown as mean ± SD, n = 12 animals/group. ^∗p < 0.05, ^∗∗p < 0.01.