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Expression of HMOX1 and SOD2 in SH-SY5Y cells. A. MPP+ up-regulated the expression level of HMOX1, and MANF further strengthened the reaction. B. MANF significantly increased the expression level of SOD2 which was decreased by MPP+ treatment. Data are presented as mean ± S.E.M. *P<0.05, **P<0.01 vs MPP+-treated group. #P<0.05, ##P<0.01 vs control group.
