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. Author manuscript; available in PMC: 2018 Jul 21.
Published in final edited form as: ACS Chem Biol. 2017 Jun 9;12(7):1903–1912. doi: 10.1021/acschembio.6b01144

Table 1.

IC50 and cLogP values for initial hits.

Compound IC50 (μM)a Predicted cLogPb
1 3.5 ± 0.6 1.72
2 4.6 ± 0.2 1.68
3 7.5 ± 1.2 3.99
4 4.1 ± 0.5 1.55
5 2.5 ± 1.2 1.45
a

Values represent mean ± SEM of three separate experiments performed in triplicate.

b

cLogP values provided by ChemBridge.