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. 2018 Jun 7;19:444. doi: 10.1186/s12864-018-4641-x

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Coverage distributions. a-c Percentage of cytosines with X coverage (strand-specific). d-f Percentage of cytosines with missing data (red) and “uninformative” coverage (green), defined as less than three reads