Fig. 3.

Comparison of HDL functions promotes more cholesterol accumulation in macrophage and reduced the anti-oxidative activity. a The levels of TC and FC contents in WT mouse macrophages incubated with SR-BI^+/+ HDL or SR-BI^−/− HDL were examined. n = 3, b comparison of PON1 activity in HDL (n = 3) and in plasma (n = 20), and plasma MPO activity (n = 20). c Oxidative/anti-oxidative properties of HDL isolated by ultracentrifugation (left, n = 3) and plasma HDL (right, n = 8) were analyzed, *P < 0.05, **P < 0.01 versus SR-BI^+/+ HDL. Values < 1.0 indicated anti-oxidative HDL, values > 1.0 indicated oxidative HDL