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. 2018 Jun 7;15:99. doi: 10.1186/s12985-018-1009-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Survival rate and weight changes of guinea pigs throughout the experiment. Three groups of Hartley guinea pigs (n = 4/group) were immunized intraperitoneally in the right flank with 3 × 10⁴ TCID₅₀ of Candid #1, 4 × 10³ TCID₅₀ of r3MACV or PBS (control). Simultaneously, in the left flank, a lethal challenge (10⁴ TCID₅₀ of JUNV strain Espindola) was injected intraperitoneally. a Their survival rate and b-d weight were observed for 28 days thereafter. The † indicated animals that either succumbed to the infection or were humanly euthanized before the end of the experiment