Table 1.
Frequencies of RPE phenotypes in drusenoid pigment epithelial detachment
| RPE morphology* | Locations at each grade | Associated with migrated RPE | Not associated with migrated RPE | |||
|---|---|---|---|---|---|---|
| Not gradable | 2 | 0.5% | 0 | 0.0% | 2 | 0.5% |
| Uniform | 22 | 5.5% | 0 | 0.0% | 22 | 5.5% |
| Non-Uniform | 237 | 59.0% | 2 | 0.5% | 235 | 58.5% |
| Very Non-Uniform | 49 | 12.2% | 4 | 1.0% | 45 | 11.2% |
| Sloughing | 16 | 4.0% | 1 | 0.2% | 15 | 3.7% |
| Shedding | 10 | 2.5% | 0 | 0.0% | 10 | 2.5% |
| Vacuolated | 2 | 0.5% | 0 | 0.0% | 2 | 0.5% |
| Intraretinal** | 15 | 3.7% | -- | -- | -- | -- |
| Vitelliform | 47 | 11.7% | 18 | 4.5% | 29 | 7.2% |
| Atrophy with BLamD | 1 | 0.2% | 1 | 0.2% | 0 | 0.0% |
| Dissociated | 1 | 0.2% | 1 | 0.2% | 0 | 0.0% |
| Atrophy without BLamD | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% |
| Total | 402 | 100.0% | 42 | 10.4% | 360 | 89.6% |
*
Phenotypes were originally assigned per Zanzottera et al 12. Vitelliform was demonstrated by Chen et al 14 and signifies RPE organelles exploded into the extracellular space, possibly accompanied by intact RPE cell bodies.
**
The Intraretinal morphology is, by definition, migrated RPE. BLamD, basal laminar deposit