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. 2018 Jan 5;50(1):e418. doi: 10.1038/emm.2017.159

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Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Gene expression patterns of the co-expressed gene set of FOXM1 and the overall survival of HCC patients in the exploration data set (n=100). (a) Gene expression patterns of FOXM1 and its associated genes. A total of 1,185 genes with expression patterns that highly correlated with FOXM1 were selected for cluster analysis. The patients were divided into two subgroups: FOXM1-high (FH) and FOXM1-low (FL). (b) Kaplan–Meier plot of the overall survival of HCC patients, stratified by the co-expressed gene set of FOXM1. The survival rate of the FH subgroup was significantly worse than that of the FL subgroup (P=0.01 by log-rank test).