Table 1. The clinical subtypes and molecular classification of breast cancer cell lines used in this study (adapted from references [24,25]).
Cell line | Classification / subtype | Tumorigenicity | Receptor expression |
---|---|---|---|
MDA-MB-231 | Claudin low[24]; basal-like[25] | Tumorigenic | ER -, PR -, HER2 - |
MCF-7 | Luminal A[24,25] | Tumorigenic | ER +, PR +/-, HER2 - |
ZR-75-1 | Luminal B[24]; luminal A[25] | Tumorigenic | ER +, PR +/-, HER2 +/- |
MCF-10A | Basal-like[25] | Non-tumorigenic | ER -, PR -, HER2 - |
ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.