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. 2018 May 24;13(5):e0196998. doi: 10.1371/journal.pone.0196998

Table 1. The clinical subtypes and molecular classification of breast cancer cell lines used in this study (adapted from references [24,25]).

Cell line Classification / subtype Tumorigenicity Receptor expression
MDA-MB-231 Claudin low[24]; basal-like[25] Tumorigenic ER -, PR -, HER2 -
MCF-7 Luminal A[24,25] Tumorigenic ER +, PR +/-, HER2 -
ZR-75-1 Luminal B[24]; luminal A[25] Tumorigenic ER +, PR +/-, HER2 +/-
MCF-10A Basal-like[25] Non-tumorigenic ER -, PR -, HER2 -

ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.