Figure 1.

Study design overview. Timeline of the experimental design indicating the dietary switch prior to the natural breeding season and the study time points. Maternal metabolic measurements (DEXA and ivGTT) and imaging studies consisting of ultrasound, amniocentesis, and blood sampling are indicated. Animals were allowed to deliver naturally at term and offspring were followed postnatally until 7 months of age. DEXA indicates dual-energy X-ray absorptiometry; G, gestational day; ivGTT, intravenous glucose tolerance tests; P, postnatal day.